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Thermo Fisher
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Addgene inc
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OriGene
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Promega
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Promega
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Genechem
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Promega
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Genechem
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Yeasen Biotechnology
lxre luciferase reporter vector plasmid ![]() Lxre Luciferase Reporter Vector Plasmid, supplied by Yeasen Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more https://www.bioz.com/result/lxre luciferase reporter vector plasmid/product/Yeasen Biotechnology Average 90 stars, based on 1 article reviews
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Promega
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Promega
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Image Search Results
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: ( A ) Schematic structure of SLC31A1 gene and linkage disequilibrium of its candidate SNPs (color intensity is proportional to D ′ and percent numbers represent r 2 ). ( B ) Local sequence of SLC31A1 3′UTR annotated with the close locations of rs10759637 and two putative binding sites for hsa-miR-29 family. ( C ) Comparison of secondary structures, built with RNAfold program, of the local SLC31A1 3′UTRs harboring hsa-miR-29 binding sites and the wild or the variant alleles of rs10759637. ( D ) Luciferase reporter assays in 16HBE cells to analyze the regulatory role hsa-miR-29 on SLC31A1 3′UTR that could be modulated by rs10759637. Co-transfection with hsa-miR-29 member (a, b, or c) and SLC31A1 3′UTR construct consistently resulted in reduced luciferase activity. In the cases of hsa-miR-29 b or c, rs10759637 allelic state significantly affected the cis -regulation toward reporter expression. ( E ) Real-time quantitative RT-PCR analysis of SLC31A1 mRNA expression in lung tumorous tissues from an independent cohort of patients, which was significantly correlated with rs10759637 genotypes.
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques: Sequencing, Binding Assay, Variant Assay, Luciferase, Cotransfection, Construct, Activity Assay, Expressing, Quantitative RT-PCR
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: Association between SLC31A1 SNPs and toxicity outcomes
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques:
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: Stratification analysis of association between SLC31A1 SNPs and toxicity outcomes
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques:
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: Association between SLC31A1 SNPs and survival
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques:
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: Stratification analysis of association between SLC31A1 SNPs and overall survival
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques: Variant Assay
Journal: Oncotarget
Article Title: Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation
doi: 10.18632/oncotarget.24794
Figure Lengend Snippet: In the entire patients ( A ) and subgroups stratified respectively with gender ( B ), age ( C ), smoking status ( D ), ECOG performance status ( E ), and histological type ( F ), the curves were plotted with SPSS software according to genotypes of two SNPs. For rs2233914, the A/A homozygote was compared to the G/G+G/A group as reference. For rs10759637, the A/C heterozygote was compared to the A/A+C/C homozygotes group as reference.
Article Snippet: Human bronchial epithelial cell line 16HBE (1.0 × 10 5 cells) was cotransfected with wild or
Techniques: Software